Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367551 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL31222313 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL31222308 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL24373426 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL5475986 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL31339870 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423219 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL31339909 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1GAAPOLBKMT2A | |
| SCHEMBL335655 | 0.80 | FLT3 (0.68) | KDM4EFLT3PDGFRBPDGFRAHSD17B10 | |
| SCHEMBL30189510 | 0.80 | FLT3 (0.68) | KDM4EFLT3PDGFRBPDGFRAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705297-A1 | SMALL MOLECULE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2024229205-A1 | SMALL MOLECULE THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | WO | disclosed |