Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423094 | 0.88 | KDM4E (0.45) | KDM4EGAAALDH1A1POLBRUNX1 | |
| SCHEMBL30548989 | 0.86 | KDM4E (0.45) | KDM4EGAAALDH1A1POLBRUNX1 | |
| SCHEMBL31339870 | 0.84 | KDM4E (0.55) | KDM4EGAAALDH1A1POLBKMT2A | |
| SCHEMBL31423261 | 0.83 | ALDH1A1 (0.50) | KDM4EGAAALDH1A1POLBKMT2A | |
| SCHEMBL31423379 | 0.82 | KDM4E (0.39) | KDM4EGAAALDH1A1POLBRUNX1 | |
| SCHEMBL29457828 | 0.81 | KDM4E (0.56) | KDM4EGAAALDH1A1RUNX1EGLN1 | |
| SCHEMBL17310806 | 0.81 | KDM4E (0.56) | KDM4EGAAALDH1A1RUNX1EGLN1 | |
| SCHEMBL31222326 | 0.81 | KDM4E (0.78) | KDM4EGAAALDH1A1POLBKMT2A | |
| SCHEMBL3714878 | 0.80 | KDM4E (0.46) | KDM4EGAAALDH1A1KMT2APTGS1 | |
| SCHEMBL1367463 | 0.79 | KDM4E (0.56) | KDM4EGAAALDH1A1POLBRUNX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| EP-4501912-A1 | NOVEL HETEROCYCLIC COMPOUND | Shouyao Holdings (Beijing) Co., Ltd. (CN) | 2025-02-05 | — | — | EP | disclosed |