Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24373426 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAACA2 | |
| SCHEMBL31423261 | 0.86 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDGAAMAOB | |
| SCHEMBL1367551 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1HPGDGAACA2 | |
| SCHEMBL30237524 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1GAAL3MBTL1NPC1 | |
| SCHEMBL19512086 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1GAAL3MBTL1NPC1 | |
| SCHEMBL6161066 | 0.83 | ALOX15 (0.69) | KDM4EALDH1A1GAAL3MBTL1NPC1 | |
| SCHEMBL1319990 | 0.82 | RAB9A (0.80) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL31222326 | 0.82 | KDM4E (0.78) | KDM4EALDH1A1HPGDGAACA12 | |
| SCHEMBL31422797 | 0.82 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL1372751 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |