Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238859 | 0.90 | MAPT (0.58) | EGFRPTGS2MAPTMKNK1MKNK2 | |
| SCHEMBL35823 | 0.87 | PTGS2 (0.58) | EGFRPTGS2MAPTTSHRKMT2A | |
| SCHEMBL2039468 | 0.87 | CA12 (0.62) | EGFRMKNK1MKNK2TSHRKMT2A | |
| SCHEMBL29473817 | 0.87 | CA12 (0.62) | EGFRMKNK1MKNK2TSHRKMT2A | |
| SCHEMBL31238850 | 0.86 | MAPT (0.66) | MAPTTSHRKMT2AALDH1A1LMNA | |
| SCHEMBL13066266 | 0.86 | ALDH1A1 (0.58) | EGFRPTGS2MAPTKMT2AALDH1A1 | |
| SCHEMBL10296036 | 0.85 | MKNK1 (0.54) | EGFRMAPTMKNK1MKNK2KMT2A | |
| SCHEMBL6535961 | 0.85 | MAPT (0.57) | EGFRMAPTTSHRKMT2AALDH1A1 | |
| SCHEMBL10458005 | 0.85 | PTGS2 (0.76) | EGFRPTGS2MAPTTSHRKMT2A | |
| SCHEMBL17630101 | 0.84 | MAPT (0.53) | EGFRPTGS2MAPTKMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029148-A | N-phenyl-3- (2, 5-dioxopyrrolidin-1-yl) propionamide derivatives and similar compounds as DUX4 inhibitors for the treatment of, for example, neuromuscular diseases | 阿勒泰治疗公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-119013017-A | Pharmaceutical composition for treating cancer comprising an anticancer agent and a novel compound having an inhibitory activity on prostaglandin E2 receptor | 治纳辅医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |