Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22022953 | 0.65 | NISCH (0.47) | NISCH | |
| SCHEMBL2531545 | 0.63 | ALDH1A1 (0.53) | — | |
| SCHEMBL673081 | 0.63 | ALDH1A1 (0.61) | OPRM1 | |
| SCHEMBL9481032 | 0.63 | ALDH1A1 (0.61) | OPRM1 | |
| SCHEMBL13170396 | 0.63 | NISCH (0.46) | NISCH | |
| SCHEMBL158226 | 0.63 | — | — | |
| SCHEMBL30893871 | 0.63 | ALDH1A1 (0.61) | OPRM1 | |
| Dihydronicotyrine SCHEMBL1207625 | 0.61 | CYP2A6 (0.52) | NISCH | |
| SCHEMBL14853508 | 0.61 | — | — | |
| Bromide SCHEMBL28296934 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118909993-A | Imine reductase mutant and application thereof in synthesis of optically pure 2-arylpyrrolidine | 华东理工大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118909993-A | Imine reductase mutant and application thereof in synthesis of optically pure 2-arylpyrrolidine | 华东理工大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118909993-A | Imine reductase mutant and application thereof in synthesis of optically pure 2-arylpyrrolidine | 华东理工大学 | 2024-11-08 | — | — | CN | disclosed |