⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225891 | 0.95 | — | — | |
| SCHEMBL31225526 | 0.92 | BRD4 (0.30) | — | |
| SCHEMBL31225199 | 0.90 | CD22 (0.34) | — | |
| SCHEMBL31225551 | 0.89 | — | — | |
| SCHEMBL31225929 | 0.89 | — | — | |
| SCHEMBL31226010 | 0.89 | CNR1 (0.30) | — | |
| SCHEMBL31226036 | 0.87 | CD22 (0.30) | — | |
| SCHEMBL31225374 | 0.86 | DRD2 (0.32) | — | |
| SCHEMBL31454107 | 0.86 | CCR5 (0.34) | — | |
| SCHEMBL31225410 | 0.85 | CD22 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727537-A2 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | Adaxion Therapeutics, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20250064941-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | ADAXION THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
| WO-2024259007-A2 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | OSPREY BIOPHARMACEUTICALS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |