Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395492 | 1.00 | METAP2 (0.50) | METAP2NPC1RAB9AMAP4K4KIT | |
| SCHEMBL7396855 | 0.82 | MEN1 (0.46) | NPC1RAB9AMEN1KDM4ELMNA | |
| SCHEMBL7278792 | 0.81 | METAP2 (0.43) | METAP2NPC1RAB9AMAP4K4CHEK1 | |
| SCHEMBL695196 | 0.80 | CYP1A2 (0.46) | METAP2KDM4EALDH1A1HPGDXDH | |
| SCHEMBL31226415 | 0.80 | NTRK1 (0.40) | MAP4K4KITMEN1KDM4EALDH1A1 | |
| Bromide SCHEMBL7301912 | 0.79 | METAP2 (0.42) | METAP2NPC1RAB9AMAP4K4CHEK1 | |
| Hydrochloric Acid SCHEMBL7349133 | 0.79 | METAP2 (0.42) | METAP2NPC1RAB9AMAP4K4CHEK1 | |
| SCHEMBL24270330 | 0.78 | NPC1 (0.65) | METAP2NPC1RAB9AMAP4K4KIT | |
| SCHEMBL30165348 | 0.78 | NPC1 (0.65) | METAP2NPC1RAB9AMAP4K4KIT | |
| SCHEMBL7370129 | 0.77 | PTGS1 (0.50) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709712-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | Blueprint Medicines Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233900-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | BLUEPRINT MEDICINES CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |