SCHEMBL31228171

SCHEMBL31228171

O=C(Nc1ncnc2c1ccn2[C@@H]1O[C@](F)(CI)[C@@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 2/20 0.46
▸ PRMT5 O14744 8/20 0.38
▸ WDR77 Q9BQA1 8/20 0.38
▸ METTL3 Q86U44 1/20 0.38
▸ METTL14 Q9HCE5 1/20 0.38
▸ SLC29A1 Q99808 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228638 0.84 ADK (0.38) ADKPRMT5WDR77METTL3METTL14
SCHEMBL31228160 0.80 ADK (0.60) ADKPRMT5WDR77METTL3METTL14
SCHEMBL19397144 0.80 ADK (0.38) ADKPRMT5WDR77
SCHEMBL30745131 0.80 ADK (0.38) ADKPRMT5WDR77
SCHEMBL19379658 0.80 ADK (0.38) ADKPRMT5WDR77
SCHEMBL24687181 0.79 ADK (0.72) ADKMETTL3METTL14SLC29A1
SCHEMBL23023836 0.79 ADK (0.72) ADKMETTL3METTL14SLC29A1
SCHEMBL31123791 0.79 ADK (0.72) ADKMETTL3METTL14SLC29A1
SCHEMBL25410585 0.79 ADK (0.60) ADKMETTL3METTL14SLC29A1
SCHEMBL31167393 0.79 ADK (0.60) ADKMETTL3METTL14SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
Send feedback