SCHEMBL31228240

SCHEMBL31228240

C[C@]1(O)[C@H](n2ccc3c(N)ncnc32)O[C@](F)(CO)[C@H]1O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 19/20 0.52
WDR77 Q9BQA1 19/20 0.52
ADK P55263 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150861 0.87 PRMT5 (0.56) PRMT5WDR77ADK
SCHEMBL12154578 0.87 PRMT5 (0.56) PRMT5WDR77ADK
SCHEMBL733579 0.87 PRMT5 (0.56) PRMT5WDR77ADK
SCHEMBL31228121 0.86 ADK (0.46) PRMT5WDR77ADK
SCHEMBL21078499 0.86 PRMT5 (0.44) PRMT5WDR77ADK
SCHEMBL19379667 0.85 PRMT5 (0.43) PRMT5WDR77ADK
SCHEMBL19379660 0.85 PRMT5 (0.43) PRMT5WDR77ADK
SCHEMBL19859341 0.85 PRMT5 (0.46) PRMT5WDR77ADK
SCHEMBL19859757 0.85 PRMT5 (0.46) PRMT5WDR77ADK
SCHEMBL19859805 0.82 ADORA2A (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO disclosed