SCHEMBL31228281

SCHEMBL31228281

[N-]=[N+]=N[C@]1(CI)O[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADK P55263 1/20 0.50
PRMT5 O14744 16/20 0.45
WDR77 Q9BQA1 13/20 0.45
METTL3 Q86U44 1/20 0.41
DNMT1 P26358 1/20 0.41
DNMT3B Q9UBC3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228138 0.91 ADK (0.51) ADKPRMT5WDR77METTL3DNMT1
SCHEMBL31228198 0.76 ADK (0.57) ADKPRMT5WDR77METTL3
SCHEMBL31228504 0.75 ADK (0.47) ADKPRMT5WDR77METTL3
SCHEMBL16214128 0.75 AHCY (0.54) PRMT5WDR77
SCHEMBL31228199 0.75 ADK (0.40) ADKPRMT5WDR77METTL3
SCHEMBL29548998 0.73 AHCY (0.59) PRMT5WDR77
SCHEMBL13523527 0.73 AHCY (0.59) PRMT5WDR77
SCHEMBL13471035 0.72 ADORA2A (0.48) ADKPRMT5WDR77METTL3
SCHEMBL16214138 0.72 SLC28A1 (0.48)
SCHEMBL31228134 0.72 ADK (0.55) ADKPRMT5WDR77METTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 WO disclosed