SCHEMBL31228484

SCHEMBL31228484

CSc1ncnc2c1ncn2[C@@H]1O[C@](F)(CO)[C@@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 1/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ PDE4A P27815 1/20 0.47
▸ PDE4B Q07343 1/20 0.47
▸ PDE4C Q08493 1/20 0.47
▸ PDE4D Q08499 1/20 0.47
▸ SLC29A1 Q99808 16/20 0.44
▸ PRMT5 O14744 1/20 0.43
▸ WDR77 Q9BQA1 1/20 0.43
▸ STAT6 P42226 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13844404 0.83 PRMT5 (0.61) SMN1; SMN2SLC29A1PRMT5WDR77STAT6
SCHEMBL31228232 0.81 SLC29A1 (0.44) SLC29A1PRMT5WDR77
SCHEMBL25390968 0.76 ADORA3 (0.57) SMN1; SMN2SLC29A1PRMT5WDR77STAT6
SCHEMBL25388043 0.76 ADORA3 (0.57) SMN1; SMN2SLC29A1PRMT5WDR77STAT6
SCHEMBL26239618 0.76 ADORA3 (0.57) SMN1; SMN2SLC29A1PRMT5WDR77STAT6
SCHEMBL240981 0.76 SMN1; SMN2 (0.77) TP53SMN1; SMN2SLC29A1STAT6
SCHEMBL672036 0.76 SMN1; SMN2 (0.77) TP53SMN1; SMN2SLC29A1STAT6
SCHEMBL7134319 0.76 SMN1; SMN2 (0.77) TP53SMN1; SMN2SLC29A1STAT6
SCHEMBL30089484 0.76 SMN1; SMN2 (0.77) TP53SMN1; SMN2SLC29A1STAT6
SCHEMBL672035 0.76 SMN1; SMN2 (0.77) TP53SMN1; SMN2SLC29A1STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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