SCHEMBL31228562

SCHEMBL31228562

OC[C@@]1(F)O[C@@H](n2ccc3cncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 5/20 0.44
▸ WDR77 Q9BQA1 3/20 0.44
▸ ADA P00813 1/20 0.33
▸ ADK P55263 3/20 0.32
▸ NNMT P40261 1/20 0.31
▸ MKNK2 Q9HBH9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228076 0.79 ADK (0.41) PRMT5WDR77ADK
SCHEMBL31228198 0.78 ADK (0.57) PRMT5WDR77ADK
SCHEMBL31228235 0.78 PRMT5 (0.44) PRMT5WDR77ADK
SCHEMBL31228144 0.78 PRMT5 (0.44) PRMT5WDR77ADK
SCHEMBL31228185 0.78 PRMT5 (0.51) PRMT5WDR77
SCHEMBL31228183 0.77 CDK1 (0.35) ADAADK
SCHEMBL31228497 0.77 ADK (0.33) PRMT5WDR77ADAADK
SCHEMBL31228142 0.76 CDK1 (0.39) ADAADK
SCHEMBL31228151 0.75 PRMT5 (0.40) PRMT5WDR77ADK
SCHEMBL31228186 0.75 PRMT5 (0.46) PRMT5WDR77ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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