Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 8/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228880 | 0.87 | HTT (0.42) | GRM2MAPTHTTHRH4APP | |
| SCHEMBL17809488 | 0.82 | GRM2 (0.46) | GRM2MAT2AHRH4CYP3A4CYP2C9 | |
| SCHEMBL30138914 | 0.79 | NPC1 (0.48) | GRM2MAPTHTTMAT2ANPC1 | |
| SCHEMBL31241270 | 0.78 | MAT2A (0.37) | GRM2HTTMAT2ACYP3A4CYP2C9 | |
| SCHEMBL17809495 | 0.78 | GRM2 (0.58) | GRM2HTTMEN1ALDH1A1KMT2A | |
| SCHEMBL6921733 | 0.77 | HRH4 (0.46) | HTTHRH4APPCYP2C19MEN1 | |
| SCHEMBL25643935 | 0.77 | AAK1 (0.43) | MAT2AMEN1KMT2A | |
| SCHEMBL21320757 | 0.76 | ALDH1A1 (0.46) | MAPTHTTAPPMEN1NPC1 | |
| SCHEMBL24329884 | 0.75 | MEN1 (0.51) | MAPTHTTAPPMEN1NPC1 | |
| SCHEMBL29878230 | 0.75 | MAT2A (0.36) | GRM2MAPTMAT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192200-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118724899-A | 2 (1H) -quinoxalinone compounds, pharmaceutical compositions and uses thereof | 中国药科大学 | 2024-10-01 | — | — | CN | disclosed |