Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091134 | 0.94 | KDM4E (0.65) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL11185030 | 0.90 | KDM4E (0.71) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL312380 | 0.88 | KDM4E (0.84) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL312663 | 0.88 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL10739914 | 0.88 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL312379 | 0.87 | KDM4E (0.76) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL311638 | 0.87 | KDM4E (0.67) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10738181 | 0.87 | KDM4E (0.69) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL312122 | 0.86 | KDM4E (0.72) | KDM4EHSD17B10HPGDALDH1A1PMP22 | |
| SCHEMBL312030 | 0.86 | KDM4E (0.69) | KDM4EHSD17B10HPGDALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473568-A | ANTIBACTERIAL AGENTS | WARNER LAMBERT COMPANY (US) | 1984-09-25 | — | — | US | claimed |
| US-8093381-B2 | Method of synthesis of fluoroquinolones | BIOCODEX (FR) | 2012-01-10 | — | — | US | disclosed |
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | BIOCODEX (FR) | 2009-02-26 | — | — | US | disclosed |
| US-4473568-A | ANTIBACTERIAL AGENTS | WARNER LAMBERT COMPANY (US) | 1984-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | NQO2, Q6ZSR9, QARS1 | KDM4E 2435/4885HSD17B10 1768/4885HPGD 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.