Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20489475 | 1.00 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL2666809 | 0.83 | PIK3CA (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL31229386 | 0.83 | PIK3CA (0.45) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL31229365 | 0.81 | PIK3CA (0.45) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL20489690 | 0.80 | ALDH1A1 (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL30526543 | 0.73 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL184566 | 0.73 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL20489574 | 0.73 | AADAT (0.45) | ALDH1A1HSD17B10TSHRAADATSMN1; SMN2 | |
| SCHEMBL558626 | 0.73 | HSD17B10 (0.41) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL31318718 | 0.73 | HSD17B10 (0.41) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024230578-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-11-14 | — | — | WO | disclosed |