Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229592 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL31229697 | 0.82 | MCL1 (0.43) | ALDH1A1GAAHPGDKDM4EMAPT | |
| SCHEMBL69502 | 0.80 | DAO (0.51) | ALDH1A1GAAHPGDMEN1KMT2A | |
| SCHEMBL31229651 | 0.75 | KDM4E (0.42) | ALDH1A1GAAHPGDKDM4EPARP1 | |
| SCHEMBL31229812 | 0.73 | KDM4E (0.43) | ALDH1A1GAAHPGDKDM4EUCHL1 | |
| SCHEMBL31229599 | 0.72 | KDM4E (0.42) | ALDH1A1GAAHPGDKDM4EUCHL1 | |
| SCHEMBL31229802 | 0.72 | HSD17B10 (0.46) | ALDH1A1GAAHPGDKDM4EUCHL1 | |
| SCHEMBL31229807 | 0.72 | KDM4E (0.39) | ALDH1A1GAAHPGDKDM4EPARP1 | |
| SCHEMBL9098195 | 0.71 | ERCC5 (0.48) | ALDH1A1GAAHPGDKDM4EERCC5 | |
| SCHEMBL4146436 | 0.71 | DAO (0.61) | ALDH1A1GAAHPGDKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |