Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 7/20 | 0.36 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229651 | 0.76 | KDM4E (0.42) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31229802 | 0.76 | HSD17B10 (0.46) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31229575 | 0.75 | KDM4E (0.41) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31229807 | 0.73 | KDM4E (0.39) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31229507 | 0.72 | LMNA (0.40) | POLB | |
| SCHEMBL31229776 | 0.72 | ALDH1A1 (0.49) | KDM4EHPGDGAAALDH1A1POLB | |
| SCHEMBL31229697 | 0.70 | MCL1 (0.43) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31229841 | 0.70 | UCHL1 (0.44) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL12616745 | 0.70 | — | — | |
| SCHEMBL4146436 | 0.69 | DAO (0.61) | KDM4EHSD17B10HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |