Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25210667 | 1.00 | MAPT (0.59) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL25210666 | 1.00 | MAPT (0.59) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL25207048 | 0.99 | MAOB (0.58) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL25207050 | 0.99 | MAOB (0.58) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL30382112 | 0.99 | MAOB (0.58) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL8881800 | 0.81 | MAOB (0.55) | MAPTMAOBLMNACYP3A4HSD17B10 | |
| SCHEMBL8881795 | 0.81 | MAOB (0.55) | MAPTMAOBLMNACYP3A4HSD17B10 | |
| SCHEMBL27706696 | 0.81 | MAPT (0.58) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL28816886 | 0.80 | PPARG (0.50) | MAPTMAOBMEN1ALDH1A1KMT2A | |
| SCHEMBL28816885 | 0.80 | PPARG (0.50) | MAPTMAOBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |