Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | ICMT | O60725 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8881800 | 1.00 | MAOB (0.55) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL8882340 | 0.86 | TRPV1 (0.50) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL8882335 | 0.86 | TRPV1 (0.50) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL15970448 | 0.83 | PTPN1 (0.57) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL15970225 | 0.83 | PTPN1 (0.57) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL15970447 | 0.83 | PTPN1 (0.57) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL14248732 | 0.83 | PTPN1 (0.57) | MAOBBACE1PTPN1APPCNR2 | |
| SCHEMBL25207048 | 0.83 | MAOB (0.58) | MAOBPTPN1APPLMNACYP3A4 | |
| SCHEMBL30382112 | 0.83 | MAOB (0.58) | MAOBPTPN1APPLMNACYP3A4 | |
| SCHEMBL25207050 | 0.83 | MAOB (0.58) | MAOBPTPN1APPLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | claimed |
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |