Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285110 | 1.00 | CYP19A1 (0.66) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL25214881 | 0.93 | MEN1 (0.71) | CYP19A1ABCG2MEN1KMT2AALDH1A1 | |
| SCHEMBL25221504 | 0.91 | CYP19A1 (0.67) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL25190979 | 0.91 | CYP19A1 (0.61) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL30383841 | 0.91 | CYP19A1 (0.61) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL25191661 | 0.90 | CYP19A1 (0.63) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL25234192 | 0.90 | CYP19A1 (0.63) | CYP19A1ABCG2MEN1KMT2AMAOB | |
| SCHEMBL25193206 | 0.90 | MEN1 (0.76) | CYP19A1ABCG2MEN1KMT2AALDH1A1 | |
| SCHEMBL25190643 | 0.90 | CTSL (0.67) | CYP19A1ABCG2MEN1KMT2AALDH1A1 | |
| SCHEMBL25219723 | 0.90 | CYP19A1 (0.66) | CYP19A1ABCG2MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |