Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 17/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 15/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126661 | 1.00 | PRKCQ (0.43) | PRKCQPRKCDIMPDH2IMPDH1BRD4 | |
| SCHEMBL3726444 | 0.79 | PRKCQ (0.46) | PRKCQPRKCDBRD4 | |
| SCHEMBL30774499 | 0.73 | BRD4 (0.49) | PRKCQPRKCDIMPDH2IMPDH1BRD4 | |
| SCHEMBL403956 | 0.72 | IMPDH2 (0.57) | PRKCQPRKCDIMPDH2IMPDH1 | |
| SCHEMBL30309353 | 0.72 | IMPDH2 (0.57) | PRKCQPRKCDIMPDH2IMPDH1 | |
| SCHEMBL22482294 | 0.72 | CCNT1 (0.62) | IMPDH2IMPDH1 | |
| SCHEMBL3073580 | 0.71 | PIK3CD (0.46) | PRKCQPRKCD | |
| SCHEMBL19475693 | 0.71 | METAP2 (0.38) | — | |
| SCHEMBL30430699 | 0.70 | BRD4 (0.35) | PRKCQPRKCDBRD4 | |
| SCHEMBL23937722 | 0.69 | BRD4 (0.45) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705292-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024233360-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |