Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.58 |
| ▸ | RXRB | P28702 | 3/20 | 0.58 |
| ▸ | RXRG | P48443 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | ADH5 | P11766 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20497100 | 0.91 | RXRA (0.62) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL23302210 | 0.89 | ADH5 (0.63) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL28670680 | 0.87 | ADH5 (0.61) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL21271818 | 0.84 | RXRA (0.50) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL16255738 | 0.83 | AKR1C3 (0.60) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL8141484 | 0.83 | GLA (0.58) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL29869199 | 0.81 | EPHX2 (0.55) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL566127 | 0.81 | EPHX2 (0.55) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL20497045 | 0.81 | RXRA (0.58) | RXRARXRBRXRGAKR1C3AKR1C2 | |
| SCHEMBL8437529 | 0.81 | ADH5 (0.59) | RXRARXRBRXRGAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240424488-A1 | High-Entropy Metal-Organic Frameworks | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC | 2024-12-26 | — | — | US | disclosed |