Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874833 | 0.82 | MAOB (0.44) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL6008 | 0.82 | MAOB (0.44) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL8786731 | 0.75 | MAOB (0.39) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| Methylchromone SCHEMBL25934 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL21936757 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| Methylchromone SCHEMBL29387804 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL294155 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL11740470 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL76091 | 0.75 | MAOB (0.61) | MAOBMAOAPTPN1ALDH1A1KDM4E | |
| SCHEMBL11235545 | 0.75 | MAOB (0.56) | MAOBMAOAPTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285925-A | Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism | 中国科学院新疆理化技术研究所 | 2023-12-26 | — | — | CN | claimed |
| CN-115745978-A | Chromone-based organic small molecule, method and organic small molecule dual-emission intensity and service life-based dual-ratio temperature sensor | 中国科学院大学 | 2023-03-07 | — | — | CN | claimed |
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117285925-A | Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism | 中国科学院新疆理化技术研究所 | 2023-12-26 | — | — | CN | disclosed |
| CN-113087722-B | Tricyclic isoxazole compound and preparation method and application thereof | 中国人民解放军海军军医大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115745978-A | Chromone-based organic small molecule, method and organic small molecule dual-emission intensity and service life-based dual-ratio temperature sensor | 中国科学院大学 | 2023-03-07 | — | — | CN | disclosed |
| US-20210293825-A1 | METHODS FOR PRECISION THERAPEUTIC TARGETING OF HUMAN CANCER CELL MOTILITY AND KITS THEREOF | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-09-23 | — | — | US | disclosed |
| US-20210293825-A1 | METHODS FOR PRECISION THERAPEUTIC TARGETING OF HUMAN CANCER CELL MOTILITY AND KITS THEREOF | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-09-23 | — | — | US | disclosed |
| CN-109438471-B | Tricyclic isoxazole compound and preparation method and application thereof | 中国人民解放军第二军医大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113087722-A | Tricyclic isoxazole compound and preparation method and application thereof | 中国人民解放军海军军医大学 | 2021-07-09 | — | — | CN | disclosed |
| EP-0866692-A1 | USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1998-09-30 | — | — | EP | disclosed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| WO-1997021432-A1 | USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK | LABORATOIRE INNOTHERA, S.A. (FR) | 1997-06-19 | — | — | WO | disclosed |
| CN-1148593-A | Production method for chromone derivative and its medicinal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-04-30 | — | — | CN | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |