Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.78 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.78 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.78 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | F2 | P00734 | 1/20 | 0.78 |
| ▸ | PLAU | P00749 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydroisorhamnetin SCHEMBL16887921 | 1.00 | CYP2C9 (0.78) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| Dihydroisorhamnetin SCHEMBL30255782 | 1.00 | CYP2C9 (0.78) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| Dihydroisorhamnetin SCHEMBL30915472 | 1.00 | CYP2C9 (0.78) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| SCHEMBL28460634 | 0.93 | CYP2C9 (0.68) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| SCHEMBL19789557 | 0.93 | XDH (0.70) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| SCHEMBL21422528 | 0.92 | MAPT (0.79) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| Tamaraxetin SCHEMBL16887881 | 0.91 | CYP3A4 (0.73) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| Tamaraxetin SCHEMBL30256267 | 0.91 | CYP3A4 (0.73) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| Tamaraxetin SCHEMBL18235875 | 0.91 | CYP3A4 (0.73) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 | |
| SCHEMBL21738290 | 0.89 | CYP2C9 (0.67) | CYP2C9CYP3A4ALOX15SLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |