Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238455 | 0.89 | SIGMAR1 (0.73) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL31238411 | 0.86 | SIGMAR1 (0.87) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL7933564 | 0.84 | SIGMAR1 (0.73) | SIGMAR1MAPTKDM4EABCB1ABCG2 | |
| SCHEMBL7605927 | 0.84 | MAPT (0.73) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL31238446 | 0.83 | ABCB1 (0.85) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL31238451 | 0.83 | MAPT (0.77) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL28647889 | 0.81 | SIGMAR1 (0.78) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL10627793 | 0.81 | ABCG2 (0.58) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL8786926 | 0.81 | SIGMAR1 (0.78) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL31238530 | 0.81 | TNKS (0.66) | SIGMAR1MAPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189504-A1 | BROAD - SPECTRUM ANTI VIRAL COMPOUNDS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2024-09-19 | — | — | WO | claimed |
| WO-2024189504-A1 | BROAD - SPECTRUM ANTI VIRAL COMPOUNDS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2024-09-19 | — | — | WO | disclosed |