Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.68 |
| ▸ | STS | P08842 | 1/20 | 0.63 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835584 | 0.86 | SIGMAR1 (0.76) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27816181 | 0.86 | MAPT (0.70) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28632889 | 0.86 | ABCB1 (0.73) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28647889 | 0.84 | SIGMAR1 (0.78) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL31238513 | 0.84 | SIGMAR1 (0.65) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8786926 | 0.83 | SIGMAR1 (0.78) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28646380 | 0.83 | ABCB1 (0.68) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8786565 | 0.82 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL27835673 | 0.82 | MAPT (0.64) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8786494 | 0.82 | SIGMAR1 (0.77) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |