Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16546620 | 1.00 | CTSK (0.48) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL937622 | 0.89 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL17093839 | 0.89 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2441956 | 0.89 | CTSK (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13422138 | 0.88 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL21096421 | 0.88 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL27041516 | 0.88 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL14820491 | 0.86 | CTSK (0.59) | CTSKCTSS | |
| SCHEMBL4416484 | 0.86 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL1162230 | 0.86 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705299-A1 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | Rayzebio, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024229154-A1 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | RAYZEBIO, INC. (US) | 2024-11-07 | — | — | WO | disclosed |