Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27041516 | 1.00 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL21096421 | 1.00 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL27133818 | 0.90 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13422140 | 0.90 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL16387553 | 0.90 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL16546620 | 0.88 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL31240143 | 0.88 | CTSK (0.48) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3378213 | 0.87 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3585273 | 0.87 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3570961 | 0.87 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20250213705-A1 | PSMA TARGETING LIGANDS AND METHODS OF USE | BRIGHT PEAK THERAPEUTICS AG (CH) | 2025-07-03 | — | — | US | disclosed |
| EP-4558513-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | Merck Sharp & Dohme LLC (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2025041103-A1 | PSMA TARGETING LIGANDS AND METHODS OF USE | BRIGHT PEAK THERAPEUTICS AG (CH) | 2025-02-27 | — | — | WO | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024020159-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | MERCK SHARP & DOHME LLC (US) | 2024-01-25 | — | — | WO | disclosed |
| US-9556119-B2 | Process for preparing desmosine, isodesmosine, and derivatives thereof | SOPHIA SCHOOL CORPORATION (JP) | 2017-01-31 | — | — | US | disclosed |
| US-20150376127-A1 | PROCESS FOR PREPARING DESMOSINE, ISODESMOSINE, AND DERIVATIVES THEREOF | SOPHIA SCHOOL CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| WO-2010043867-A1 | PYRROLO [2, 3-D] PYRIMIDINES AS INHIBITORS OF HSP90 | CHROMA THERAPEUTICS LTD (GB) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376127-A1 | PROCESS FOR PREPARING DESMOSINE, ISODESMOSINE, AND DERIVATIVES THEREOF | SI, SMS, SRM | CTSK 1451/4885CTSS 880/4885CA1 300/4885 |
| US-20250213705-A1 | PSMA TARGETING LIGANDS AND METHODS OF USE | FOLH1, KLK3, PSMA2 | CTSK 722/4885CTSS 491/4885CA1 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.