Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.58 |
| ▸ | CLK2 | P49760 | 7/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.52 |
| ▸ | CLK3 | P49761 | 6/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240700 | 0.87 | CLK2 (0.58) | TBK1CLK2DYRK1ACLK3JAK2 | |
| SCHEMBL31240587 | 0.86 | CLK2 (0.56) | CLK2DYRK1ACLK3CCNT1CDK9 | |
| SCHEMBL31240405 | 0.85 | CLK2 (0.59) | CLK2DYRK1ACLK3JAK2 | |
| SCHEMBL31240705 | 0.85 | CLK2 (0.57) | CLK2DYRK1ACLK3JAK2 | |
| SCHEMBL31240313 | 0.83 | TBK1 (0.50) | TBK1CLK2DYRK1ACLK3 | |
| SCHEMBL31240559 | 0.83 | TBK1 (0.58) | TBK1CLK2DYRK1ACLK3 | |
| SCHEMBL31240306 | 0.82 | DYRK1A (0.71) | TBK1CLK2DYRK1ACLK3 | |
| SCHEMBL31240492 | 0.82 | DYRK1A (0.52) | CLK2DYRK1ACLK3CCNT1CDK9 | |
| SCHEMBL31240417 | 0.82 | CCNB2 (0.53) | CLK2DYRK1ACLK3 | |
| SCHEMBL31240343 | 0.81 | CLK2 (0.63) | CLK2DYRK1ACLK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |