Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.46 |
| ▸ | CLK2 | P49760 | 6/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CLK3 | P49761 | 5/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240473 | 0.91 | DYRK1A (0.51) | DYRK1ACLK2CLK3TBK1MAP4K1 | |
| SCHEMBL31240533 | 0.90 | TBK1 (0.54) | TBK1 | |
| SCHEMBL31240439 | 0.88 | DYRK1A (0.44) | DYRK1ACLK2CDK9CLK3TBK1 | |
| SCHEMBL31240553 | 0.87 | CLK2 (0.43) | DYRK1ACLK2CLK3TBK1MAP4K1 | |
| SCHEMBL31240700 | 0.85 | CLK2 (0.58) | DYRK1ACLK2CLK3TBK1JAK2 | |
| SCHEMBL31240485 | 0.82 | TBK1 (0.54) | TBK1JAK2 | |
| SCHEMBL31240343 | 0.81 | CLK2 (0.63) | DYRK1ACLK2CLK3JAK2 | |
| SCHEMBL31240628 | 0.80 | CLK2 (0.55) | DYRK1ACLK2CLK3TBK1TLR9 | |
| SCHEMBL31240589 | 0.80 | TBK1 (0.60) | DYRK1ACLK2CLK3TBK1 | |
| SCHEMBL31240586 | 0.80 | CLK2 (0.52) | DYRK1ACLK2CLK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |