Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 17/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240533 | 0.93 | TBK1 (0.54) | TBK1LRRK2 | |
| SCHEMBL31240589 | 0.91 | TBK1 (0.60) | TBK1 | |
| SCHEMBL31240416 | 0.87 | TBK1 (0.44) | TBK1LRRK2JAK2 | |
| SCHEMBL31240366 | 0.84 | TBK1 (0.52) | TBK1LRRK2 | |
| SCHEMBL31240473 | 0.83 | DYRK1A (0.51) | TBK1PDPK1LRRK2JAK2 | |
| SCHEMBL31240247 | 0.83 | JAK2 (0.67) | TBK1JAK2 | |
| SCHEMBL31240351 | 0.82 | DYRK1A (0.46) | TBK1JAK2 | |
| SCHEMBL31240700 | 0.82 | CLK2 (0.58) | TBK1JAK2 | |
| SCHEMBL31240628 | 0.80 | CLK2 (0.55) | TBK1JAK2 | |
| SCHEMBL31240412 | 0.79 | CLK2 (0.51) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |