Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.51 |
| ▸ | CHUK | O15111 | 5/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | CLK3 | P49761 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240247 | 0.92 | JAK2 (0.67) | TBK1JAK2CAMKK2CHUKMAPK8 | |
| SCHEMBL31240546 | 0.86 | CAMKK2 (0.54) | TBK1JAK2CAMKK2CHUKMAPK8 | |
| SCHEMBL31240547 | 0.86 | TBK1 (0.53) | TBK1CAMKK2CHUKMAPK8AURKA | |
| SCHEMBL31240591 | 0.86 | TBK1 (0.53) | TBK1JAK2CAMKK2CHUKMAPK8 | |
| SCHEMBL26686381 | 0.85 | JAK2 (0.60) | TBK1JAK2CAMKK2CHUKMAPK8 | |
| SCHEMBL31240550 | 0.83 | DYRK1A (0.51) | JAK2CAMKK2CHUKMAPK8AURKA | |
| SCHEMBL31240450 | 0.82 | JAK2 (0.58) | TBK1JAK2CDK9CLK2CLK3 | |
| SCHEMBL31240533 | 0.82 | TBK1 (0.54) | TBK1 | |
| SCHEMBL31240589 | 0.82 | TBK1 (0.60) | TBK1CLK2CLK3DYRK1A | |
| SCHEMBL31240700 | 0.81 | CLK2 (0.58) | TBK1JAK2CLK2CLK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |