Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.54 |
| ▸ | JAK2 | O60674 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240577 | 0.89 | LRRK2 (0.57) | LRRK2JAK2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL31240411 | 0.85 | CDC7 (0.58) | LRRK2JAK2CDC7CDK2CCNE1 | |
| SCHEMBL31240732 | 0.83 | JAK2 (0.51) | JAK2CDC7CDK2CCNE1DBF4 | |
| SCHEMBL31240408 | 0.83 | MAPK14 (0.49) | LRRK2JAK2CDC7CDK2CCNE1 | |
| SCHEMBL31240273 | 0.81 | JAK2 (0.47) | LRRK2JAK2CDC7CDK2CCNE1 | |
| SCHEMBL31240462 | 0.81 | JAK2 (0.54) | JAK2CDC7CDK2CCNE1DBF4 | |
| SCHEMBL31240476 | 0.80 | JAK2 (0.50) | LRRK2JAK2CDC7CDK2CCNE1 | |
| SCHEMBL26686356 | 0.79 | JAK2 (0.57) | LRRK2JAK2CDC7CDK2PLK4 | |
| SCHEMBL31240378 | 0.78 | JAK2 (0.51) | LRRK2JAK2KDM4ECDC7CDK2 | |
| SCHEMBL31240555 | 0.77 | JAK2 (0.55) | LRRK2JAK2CDC7CDK2PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |