Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.51 |
| ▸ | CDC7 | O00311 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240408 | 0.89 | MAPK14 (0.49) | JAK2CDC7DYRK1ACCNE1CDK2 | |
| SCHEMBL31240273 | 0.87 | JAK2 (0.47) | JAK2CDC7DYRK1ACCNE1CDK2 | |
| SCHEMBL31240411 | 0.85 | CDC7 (0.58) | JAK2CDC7MAPK1DYRK1ACCNE1 | |
| SCHEMBL31240404 | 0.84 | MAPK14 (0.52) | JAK2CDC7MAPK1DYRK1ACDK2 | |
| SCHEMBL31240395 | 0.83 | LRRK2 (0.54) | JAK2CDC7MAPK1DYRK1ACCNE1 | |
| SCHEMBL31240462 | 0.81 | JAK2 (0.54) | JAK2CDC7DYRK1ACCNE1CDK2 | |
| SCHEMBL31240440 | 0.80 | JAK2 (0.45) | JAK2CDC7DYRK1ACDK2MAPK14 | |
| SCHEMBL31240476 | 0.80 | JAK2 (0.50) | JAK2CDC7DYRK1ACCNE1CDK2 | |
| SCHEMBL12907182 | 0.79 | JAK2 (0.69) | JAK2CDC7MAPK1DYRK1ACDK2 | |
| SCHEMBL26686356 | 0.79 | JAK2 (0.57) | JAK2CDC7DYRK1ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |