Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 13/20 | 0.50 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | CDC7 | O00311 | 3/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.41 |
| ▸ | CLK2 | P49760 | 4/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
| ▸ | PLK4 | O00444 | 3/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | MARK3 | P27448 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240411 | 0.85 | CDC7 (0.58) | JAK2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL26686356 | 0.81 | JAK2 (0.57) | JAK2CDK2CDC7PDPK1CLK4 | |
| SCHEMBL31240732 | 0.80 | JAK2 (0.51) | JAK2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL31240395 | 0.80 | LRRK2 (0.54) | JAK2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL31240408 | 0.80 | MAPK14 (0.49) | JAK2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL31240378 | 0.80 | JAK2 (0.51) | JAK2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL31240555 | 0.79 | JAK2 (0.55) | JAK2CDK2CDC7PDPK1CLK4 | |
| SCHEMBL26686310 | 0.79 | JAK2 (0.55) | JAK2CDK2CDC7PDPK1CLK4 | |
| SCHEMBL26685748 | 0.79 | JAK2 (0.55) | JAK2CDK2CDC7PDPK1CLK4 | |
| SCHEMBL31240273 | 0.78 | JAK2 (0.47) | JAK2CDK2CDC7CCNE1DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |