Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.46 |
| ▸ | LOX | P28300 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839877 | 0.81 | CCNK (0.59) | HPGDKDM4EMAPTHTTLOXL2 | |
| SCHEMBL31240729 | 0.80 | CD74 (0.50) | CHUKINSRMAPK8CAMKK2 | |
| SCHEMBL31240620 | 0.79 | PRKCI (0.54) | CHUKINSRMAPK8CAMKK2AURKB | |
| SCHEMBL31240601 | 0.79 | MAP4K4 (0.51) | CHUKINSRMAPK8CAMKK2LMNA | |
| SCHEMBL31240434 | 0.79 | CHUK (0.57) | CHUKINSRMAPK8CAMKK2PRKD1 | |
| SCHEMBL31240796 | 0.76 | CHUK (0.42) | CHUKINSRMAPK8CAMKK2NUDT1 | |
| SCHEMBL2444894 | 0.74 | CCNB2 (0.64) | CHUK | |
| SCHEMBL31240751 | 0.72 | CCNB2 (0.61) | — | |
| SCHEMBL20056615 | 0.72 | HPGD (0.58) | HPGDKDM4ELMNAGAAMAPT | |
| SCHEMBL2318147 | 0.72 | CHUK (0.46) | CHUKINSRMAPK8CAMKK2PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |