Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 17/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK3 | P49761 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240708 | 0.89 | TBK1 (0.46) | TBK1 | |
| SCHEMBL31240808 | 0.85 | TBK1 (0.49) | TBK1CYP2D6 | |
| SCHEMBL31240546 | 0.84 | CAMKK2 (0.54) | TBK1GSK3BCLK2CLK3DYRK1A | |
| SCHEMBL31240417 | 0.81 | CCNB2 (0.53) | GSK3BCLK2CLK3DYRK1A | |
| SCHEMBL31240534 | 0.81 | PRMT5 (0.51) | CLK2CLK3DYRK1A | |
| SCHEMBL31240345 | 0.81 | CLK2 (0.48) | GSK3BCLK2CLK3DYRK1A | |
| SCHEMBL31240341 | 0.80 | CLK2 (0.48) | CLK2CLK3DYRK1A | |
| SCHEMBL31240700 | 0.79 | CLK2 (0.58) | TBK1CLK2CLK3DYRK1A | |
| SCHEMBL26685993 | 0.79 | GSK3B (0.44) | TBK1GSK3BCLK2CLK3DYRK1A | |
| SCHEMBL31240697 | 0.79 | CYP2D6 (0.46) | TBK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |