Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 10/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.46 |
| ▸ | CLK3 | P49761 | 8/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240528 | 0.99 | DYRK1A (0.45) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL31240342 | 0.84 | CLK2 (0.49) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL31240570 | 0.84 | DYRK1A (0.48) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL26686078 | 0.83 | DYRK1A (0.40) | CLK2DYRK1ACLK3CHUKAURKA | |
| SCHEMBL31240550 | 0.83 | DYRK1A (0.51) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL31240504 | 0.82 | DYRK1A (0.40) | CLK2DYRK1ACLK3TBK1AURKA | |
| SCHEMBL31240491 | 0.81 | CLK2 (0.53) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL31240700 | 0.81 | CLK2 (0.58) | CLK2DYRK1ACLK3TBK1 | |
| SCHEMBL31240618 | 0.80 | CLK2 (0.48) | CLK2DYRK1ACLK3CHUKINSR | |
| SCHEMBL31240587 | 0.80 | CLK2 (0.56) | CLK2DYRK1ACLK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |