Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.40 |
| ▸ | CLK2 | P49760 | 12/20 | 0.40 |
| ▸ | CLK3 | P49761 | 10/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240389 | 0.84 | CLK2 (0.42) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL31240291 | 0.84 | DYRK1A (0.43) | DYRK1ACLK2CLK3TBK1WNT1 | |
| SCHEMBL31240412 | 0.83 | CLK2 (0.51) | DYRK1ACLK2CLK3MAPK14WNT1 | |
| SCHEMBL31240560 | 0.83 | CLK2 (0.44) | DYRK1ACLK2CLK3MAPK14WNT1 | |
| SCHEMBL31240528 | 0.83 | DYRK1A (0.45) | DYRK1ACLK2CLK3AURKAAURKB | |
| SCHEMBL26686078 | 0.82 | DYRK1A (0.40) | DYRK1ACLK2CLK3AURKAPDPK1 | |
| SCHEMBL31240494 | 0.82 | CLK2 (0.46) | DYRK1ACLK2CLK3AURKAAURKB | |
| SCHEMBL31240380 | 0.80 | CLK2 (0.41) | DYRK1ACLK2CLK3CDK9TBK1 | |
| SCHEMBL31240490 | 0.79 | CLK2 (0.47) | DYRK1ACLK2CLK3MAPK14WNT1 | |
| SCHEMBL31240355 | 0.79 | CDK9 (0.41) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |