Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 18/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240348 | 0.83 | JAK2 (0.53) | TNIKJAK2MAPK10 | |
| SCHEMBL31240460 | 0.81 | JAK2 (0.52) | JAK2MAPK10 | |
| SCHEMBL31240615 | 0.80 | JAK2 (0.48) | JAK2 | |
| SCHEMBL31240469 | 0.80 | JAK2 (0.48) | JAK2 | |
| SCHEMBL31240424 | 0.80 | JAK2 (0.50) | JAK2 | |
| SCHEMBL31240573 | 0.77 | JAK2 (0.57) | JAK2MAPK10 | |
| SCHEMBL31240400 | 0.76 | JAK2 (0.57) | JAK2MAPK10 | |
| SCHEMBL31240265 | 0.76 | JAK2 (0.61) | JAK2MAPK10 | |
| SCHEMBL31240314 | 0.76 | JAK2 (0.68) | JAK2MAPK10 | |
| SCHEMBL26686340 | 0.76 | JAK2 (0.56) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |