Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240665 | 0.90 | WNT3A (0.41) | WNT3AGSK3BTTKRIOK2F11 | |
| SCHEMBL31240402 | 0.89 | ROCK1 (0.54) | WNT3ARIOK2CYP3A4ROCK1PRKACA | |
| SCHEMBL31240493 | 0.89 | WNT3A (0.57) | WNT3AGSK3BTTKRIOK2F11 | |
| SCHEMBL31240276 | 0.89 | ROCK1 (0.43) | WNT3ATTKRIOK2F11CYP3A4 | |
| SCHEMBL30633297 | 0.87 | MEN1 (0.48) | GSK3BTTKF11JAK2MEN1 | |
| SCHEMBL26686298 | 0.87 | MEN1 (0.48) | GSK3BTTKF11JAK2MEN1 | |
| SCHEMBL31240445 | 0.86 | WNT3A (0.47) | WNT3ATTKRIOK2F11ROCK1 | |
| SCHEMBL31240347 | 0.84 | PTK6 (0.49) | GSK3BTTKF11PRKACAJAK2 | |
| SCHEMBL31240382 | 0.84 | MAPK1 (0.52) | WNT3AGSK3BROCK1PRKACACLK2 | |
| SCHEMBL31240463 | 0.84 | PSEN1 (0.54) | WNT3ARIOK2ROCK1PRKACAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |