Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 12/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.54 |
| ▸ | PRKACA | P17612 | 7/20 | 0.54 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240276 | 0.90 | ROCK1 (0.43) | ROCK1CYP3A4PRKACARIOK2ROCK2 | |
| SCHEMBL31240322 | 0.90 | MAPK10 (0.58) | ROCK1RIOK2ROCK2CDK2GSK3A | |
| SCHEMBL31240545 | 0.89 | WNT3A (0.46) | ROCK1CYP3A4PRKACARIOK2GSK3A | |
| SCHEMBL31240463 | 0.88 | PSEN1 (0.54) | ROCK1PRKACARIOK2ROCK2CCNA2 | |
| SCHEMBL31240445 | 0.88 | WNT3A (0.47) | ROCK1PRKACARIOK2ROCK2CDK2 | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | RIOK2CDK2WNT3A | |
| SCHEMBL31240399 | 0.86 | JAK2 (0.54) | RIOK2ROCK2CDK2GSK3AMAPK10 | |
| SCHEMBL31240382 | 0.86 | MAPK1 (0.52) | ROCK1PRKACAROCK2CCNA2CDK2 | |
| SCHEMBL31240363 | 0.85 | ROCK2 (0.52) | ROCK1CYP3A4PRKACAROCK2CDK2 | |
| SCHEMBL31240386 | 0.85 | CDK2 (0.52) | ROCK1RIOK2CDK2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |