Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.56 |
| ▸ | CDK1 | P06493 | 2/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041244 | 1.00 | CDC7 (0.59) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL31240848 | 0.87 | CDC7 (0.59) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL30570949 | 0.86 | CDC7 (0.52) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL31240688 | 0.83 | CDK9 (0.50) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL31240751 | 0.83 | CCNB2 (0.61) | CDC7PIM1CDK9CCNB2CDK1 | |
| SCHEMBL31240696 | 0.83 | PRMT5 (0.65) | CDC7PIM1CDK9 | |
| SCHEMBL31240729 | 0.82 | CD74 (0.50) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL31240680 | 0.81 | CCNB2 (0.58) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL31240791 | 0.81 | CDC7 (0.53) | CDC7PIM1CDK9ADORA2AADORA1 | |
| SCHEMBL1777011 | 0.80 | CDC7 (0.56) | CDC7PIM1CDK9CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |