Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.59 |
| ▸ | CDC7 | O00311 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041244 | 0.83 | CDC7 (0.59) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL31240593 | 0.83 | CDC7 (0.59) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL31240688 | 0.83 | CDK9 (0.50) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL31240729 | 0.81 | CD74 (0.50) | CDC7PIM1CDK9EGFRCSF1R | |
| SCHEMBL31240664 | 0.81 | CDK9 (0.48) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL31240620 | 0.80 | PRKCI (0.54) | CDK1RIPK1CDC7PIM1CDK9 | |
| SCHEMBL20765227 | 0.80 | SCN2A (0.50) | CCNB2CDK1CCNB1CCNB3CDC7 | |
| SCHEMBL31240562 | 0.80 | CDK9 (0.47) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL2444894 | 0.80 | CCNB2 (0.64) | CCNB2CDK1CCNB1CCNB3CDC7 | |
| SCHEMBL31240784 | 0.80 | TBK1 (0.53) | CCNB2CDK1CCNB1CCNB3CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |