Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240493 | 0.88 | WNT3A (0.57) | TTKJAK2WNT3ADYRK1AWNT1 | |
| SCHEMBL30633337 | 0.86 | MAPK1 (0.60) | MAPK1RAB9AKDM4EMAPK10HSD17B10 | |
| SCHEMBL26686503 | 0.86 | MAPK1 (0.60) | MAPK1RAB9AKDM4EMAPK10HSD17B10 | |
| SCHEMBL31240251 | 0.84 | MAPK1 (0.49) | JAK2WNT3AMAPK1DYRK1AMEN1 | |
| SCHEMBL31240293 | 0.84 | CDK1 (0.49) | JAK2WNT3AMAPK1F11JAK1 | |
| SCHEMBL31240532 | 0.84 | TTK (0.51) | TTKJAK2WNT3AMAPK1MEN1 | |
| SCHEMBL31240509 | 0.83 | JAK2 (0.56) | TTKJAK2WNT3ADYRK1AWNT1 | |
| SCHEMBL31240675 | 0.83 | WNT3A (0.52) | JAK2WNT3AMEN1KMT2ASLC6A2 | |
| SCHEMBL31240445 | 0.83 | WNT3A (0.47) | TTKJAK2WNT3AMAPK1DYRK1A | |
| SCHEMBL31240378 | 0.82 | JAK2 (0.51) | JAK2MAPK1DYRK1AJAK1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |