Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 5/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240240 | 0.92 | MAPK14 (0.55) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240349 | 0.92 | WNT3A (0.50) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240714 | 0.92 | WNT3A (0.55) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240493 | 0.92 | WNT3A (0.57) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240509 | 0.92 | JAK2 (0.56) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240404 | 0.89 | MAPK14 (0.52) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240457 | 0.89 | WNT3A (0.50) | WNT3ACDK1CDK2CDK4JAK2 | |
| SCHEMBL31240322 | 0.89 | MAPK10 (0.58) | WNT3ACDK2MEN1KMT2ARAB9A | |
| SCHEMBL31240445 | 0.89 | WNT3A (0.47) | WNT3ACDK1CDK2JAK2MEN1 | |
| SCHEMBL31240433 | 0.88 | CDK1 (0.51) | WNT3ACDK1CDK2CDK4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |