Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.62 |
| ▸ | GSK3A | P49840 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.47 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240668 | 0.85 | RIOK2 (0.67) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240659 | 0.82 | RIOK2 (0.74) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240699 | 0.82 | MAPK10 (0.75) | RIOK2MAPK10GSK3AKMT2ASMN1; SMN2 | |
| SCHEMBL31240607 | 0.81 | MAPK10 (0.61) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240713 | 0.80 | RIOK2 (0.62) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240719 | 0.77 | MAPK10 (0.66) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240687 | 0.75 | RIOK2 (0.67) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL11286425 | 0.74 | GSK3A (0.54) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL31240626 | 0.73 | GSK3A (0.60) | RIOK2MAPK10GSK3AKMT2ARAB9A | |
| SCHEMBL22432119 | 0.72 | ALDH1A1 (0.55) | RIOK2MAPK10GSK3ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |