Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156922 | 0.83 | NR3C2 (0.53) | RIOK2GSK3AMAPK10ANO1NR3C2 | |
| SCHEMBL31240626 | 0.81 | GSK3A (0.60) | RIOK2GSK3AMAPK10ANO1NR3C2 | |
| SCHEMBL30368259 | 0.80 | ANO1 (0.66) | ANO1NR3C2CSF1RPDGFRBKIT | |
| SCHEMBL31240678 | 0.78 | GAA (0.62) | RIOK2GSK3AMAPK10ANO1NR3C2 | |
| SCHEMBL31240659 | 0.78 | RIOK2 (0.74) | RIOK2GSK3AMAPK10KMT2A | |
| SCHEMBL31240713 | 0.78 | RIOK2 (0.62) | RIOK2GSK3AMAPK10ANO1NR3C2 | |
| SCHEMBL31240786 | 0.77 | RIOK2 (0.62) | RIOK2GSK3AMAPK10ANO1NR3C2 | |
| SCHEMBL4199348 | 0.76 | CSF1R (0.49) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL31240480 | 0.76 | GSK3A (0.63) | RIOK2GSK3AMAPK10ANO1KMT2A | |
| SCHEMBL30368264 | 0.74 | JAK2 (0.55) | ANO1CSF1RPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |