Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.66 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.64 |
| ▸ | FLT3 | P36888 | 1/20 | 0.64 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368264 | 0.89 | JAK2 (0.55) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL30368445 | 0.84 | NTRK1 (0.51) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL30368170 | 0.84 | ANO1 (0.51) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL22528884 | 0.83 | CSF1R (0.74) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL30368230 | 0.82 | JAK2 (0.62) | ANO1JAK2JAK1TYK2KCNJ5 | |
| SCHEMBL31240720 | 0.80 | RIOK2 (0.57) | ANO1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL21198049 | 0.79 | ANO1 (1.00) | ANO1 | |
| SCHEMBL30368345 | 0.79 | JAK2 (0.52) | ANO1NR3C2JAK2JAK1TYK2 | |
| SCHEMBL22528746 | 0.79 | CSF1R (1.00) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL22528781 | 0.79 | CSF1R (0.68) | ANO1CSF1RPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171744-A1 | USE OF N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY FOR TREATING CERTAIN OCULAR DISORDERS | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-4172146-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |