Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | CLK1 | P49759 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240456 | 0.85 | PRMT5 (0.46) | CDC7PRMT5CCNT1CDK9EGFR | |
| SCHEMBL31240802 | 0.79 | PRMT5 (0.46) | CDC7PRMT5CDK9 | |
| SCHEMBL31240677 | 0.79 | PRMT5 (0.40) | CDC7PRMT5CCNT1CDK9CLK2 | |
| SCHEMBL31240471 | 0.74 | PRMT5 (0.48) | CDC7PRMT5CDK9EGFRMAPK14 | |
| SCHEMBL31240648 | 0.72 | TRPA1 (0.41) | TRPA1TRPM8EGFRMAPK14CLK1 | |
| SCHEMBL31240574 | 0.71 | CLK2 (0.51) | PRMT5CLK2DYRK1ACDK2CLK3 | |
| SCHEMBL31240543 | 0.71 | PRMT5 (0.61) | PRMT5CLK2DYRK1ACLK3 | |
| SCHEMBL31240534 | 0.71 | PRMT5 (0.51) | CDC7PRMT5EGFRCLK2DYRK1A | |
| SCHEMBL31240766 | 0.70 | AURKA (0.47) | TRPA1FGFR3CCNT1CDK9EGFR | |
| SCHEMBL31240582 | 0.69 | DYRK1A (0.49) | CDC7PRMT5FGFR3CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |